Author

Aya Nassereddine

Yale UniversityORCID 0009-0008-3314-9174Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Kerri A. DavidsoniD· 2 shared Megan C. KingiD· 2 shared Rachel RiveraiD· 2 shared Sandra SandriaiD· 2 shared Valerie HorsleyiD· 2 shared Alexander GhinceaiD· 1 shared C. Patrick LuskiD· 1 shared Changwan RyuiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Kerri A. DavidsonORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintMar 20, 2026

SUN2 mediates epigenetic remodeling to drive mechanotransduction during skin fibrosis

Aya Nassereddine, Kerri A. Davidson, Sandra Sandria…·Valerie Horsley

This study identifies SUN2 as a mediator of nuclear mechanosensing in fibrosis, showing it drives chromatin remodeling and fibrotic gene expression in response to mechanical stiffness.

1 citation

humanmouse

𝕏 PostBluesky

Cell BiologybioRxivPreprintMar 20, 2026

Loss of Sun2 ablates nuclear mechanosensing-driven extracellular matrix production and mitigates lung fibrosis

Emma Carley, Sandra Sandria, Xue Yan Peng…·Megan C. King

This study shows that loss of Sun2 reduces extracellular matrix production and prevents lung fibrosis by disrupting nuclear mechanosensing.

DOI 10.64898/2026.03.18.712778

mousehuman

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