Katherine E. Trevers

This study shows that Tenm4 expression in zebrafish retinal ganglion cells affects axonal growth, presynaptic structures, and visual performance with left-right asymmetry.

This study identifies that epithelial stem cell fate, not DNA damage, determines chemoradiotherapy response in rectal cancer by analyzing patient-derived organoids and using SPARTA to validate findings.

SAVANA improves detection of somatic structural variants and copy number aberrations in cancer using long-read sequencing with higher sensitivity and specificity than existing tools.

The paper uses single-cell and tissue transcriptomics to show the organizer is a diverse collection of signaling cell sub-populations, not a single homogeneous population.

The paper constructs a gene regulatory network for neural induction using transcriptomics and epigenomics data, revealing 175 regulators and 5,614 interactions with temporal dynamics.