Author

Çağrı Güleç

Istanbul UniversityORCID 0000-0002-1256-9574Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Cecilia W. LoiD· 1 shared Clair BaldockiD· 1 shared Daniel R. Martin· 1 shared Dieter Peter ReinhardtiD· 1 shared Elisabeth Cahill· 1 shared Joseph Mauch· 1 shared Lauren W. Wang· 1 shared Stuart A. CainiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperDevelopmental Biology

Cecilia W. LoORCID

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2 papers

Recent·Most cited

Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development

Timothy J. Mead, Daniel R. Martin, Lauren W. Wang, Stuart A. Cain, Çağrı Güleç, Elisabeth Cahill, Joseph Mauch, Dieter Peter Reinhardt, Cecilia W. Lo, Clair Baldock, Suneel S. Apte

This study shows that proteolysis of fibrillin-2 by ADAMTS6 is essential for normal skeletal development, as its absence leads to skeletal defects and reduced aggrecan and cartilage link protein.

eLife · Apr 14, 2022Peer-reviewedDevelopmental Biology

Thermodynamic stability of G-quadruplex and overlapping m6A: Position-dependent collaborators in allele frequency and fitness?

Çağrı Güleç

The paper investigates how m6A and G4 motifs interact, showing that variant positions affecting their colocalization influence thermodynamic stability and allele frequency.

bioRxiv · Apr 28, 2021 · PreprintGenetics