Author

Paul F. Robbins

National Cancer InstituteORCID 0000-0002-1260-8123Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:clustering· 1 Approach:comparative / phylogenetic analysis· 1 Approach:deep learning· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Assay:structural biology· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Brian G. PierceiD· 1 shared Chih Hao WuiD· 1 shared Daichao WuiD· 1 shared Guodong CheniD· 1 shared Helder Veras Ribeiro FilhoiD· 1 shared Melyssa CheungiD· 1 shared Roy A. MariuzzaiD· 1 shared Rui Ming YiniD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Brian G. PierceORCID

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2 papers

Recent·Most cited

ImmunologyScience AdvancesPeer-reviewedNov 22, 2024

Structural characterization and AlphaFold modeling of human T cell receptor recognition of NRAS cancer neoantigens

Daichao Wu, Rui Ming Yin, Guodong Chen…·Brian G. Pierce

The paper determines crystal structures of a TCR complex with NRAS neoantigens and uses AlphaFold to model these complexes, showing varying success across different implementations.

29 citations

humanstructural biology

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Cancer BiologyLecture notes in computer sciencePeer-reviewedJan 1, 2024

Determining Optimal Placement of Copy Number Aberration Impacted Single Nucleotide Variants in a Tumor Progression History

Chih Hao Wu, Suraj R. Joshi, Welles Robinson…·Salem Malikić

This paper introduces DETOPT, a method for accurately placing SNVs affected by CNAs in tumor progression trees, showing improved accuracy on simulated data and biologically plausible results on breast cancer metastases.

DOI 10.1007/978-1-0716-3989-4_48

humanwhole-exome sequencing

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