MDS-causing mutations of ZRSR2 impair minor intron splicing by reducing its interaction with SF3B complex
Tomoki Chiba, Eri Natsumoto, Eiji OBAYASHI, So Masaki, Satoshi Tanaka, Naoyuki Kataoka
bioRxiv · Oct 9, 2026 · PreprintMolecular Biology
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Shimane UniversityORCID 0000-0002-1270-5484Unclaimed ORCID profile · follow to get notified of new preprints
2 papers
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Tomoki Chiba, Eri Natsumoto, Eiji OBAYASHI, So Masaki, Satoshi Tanaka, Naoyuki Kataoka
bioRxiv · Oct 9, 2026 · PreprintMolecular Biology
Tomomasa Oka, Hisashi Yoshida, K. Mizutani, Eiji OBAYASHI, Sam‐Yong Park, Kenji Iwasaki
This study identifies autophosphorylation-driven activation and heme-induced deactivation mechanisms of HRI, revealing how phosphorylation and heme regulate its interaction with eIF2.
The Journal of Biochemistry · Jun 25, 2026Peer-reviewedBiochemistry