Author

Tomomasa Oka

Japan Institute for Health SecurityORCID 0000-0002-0326-0751Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Eiji OBAYASHIiD· 1 shared Hiroki Tanaka· 1 shared Hisashi YoshidaiD· 1 shared K. MizutaniiD· 1 shared Katsumi MaenakaiD· 1 shared Kenji IwasakiiD· 1 shared Masataka IzumiiD· 1 shared Mina SasakiiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBiochemistry

Eiji OBAYASHIORCID

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3 papers

Recent·Most cited

Genome-wide conservation and locus-specific coding variation in Teratoramularia rumicicola, a candidate microbial herbicide for Rumex weeds

Masataka Izumi, Tomomasa Oka

The paper characterizes the genome of Teratoramularia rumicicola, identifies functional genes and isolate-specific variations, and highlights potential virulence factors relevant to its use as a microbial herbicide.

bioRxiv · Oct 22, 2026 · PreprintGenomics

Structural basis of lenacapavir-induced HIV-1 capsid disruption during virion maturation

Hiroki Tanaka, Reina Morita, Tomomasa Oka, Minoru Fukushima, Shunsuke Kita, Mina Sasaki, Katsumi Maenaka, Shinichi Machida

This study determines the cryo-EM structure of HIV-1 capsid lattice with lenacapavir, showing how it disrupts capsid formation and function during virion maturation.

Nature Communications · Sep 22, 2026Peer-reviewedMicrobiology

Regulatory mechanism of heme-regulated inhibitor through autophosphorylation-driven activation and heme-induced deactivation

Tomomasa Oka, Hisashi Yoshida, K. Mizutani, Eiji OBAYASHI, Sam‐Yong Park, Kenji Iwasaki

This study identifies autophosphorylation-driven activation and heme-induced deactivation mechanisms of HRI, revealing how phosphorylation and heme regulate its interaction with eIF2.

The Journal of Biochemistry · Jun 25, 2026Peer-reviewedBiochemistry