Author

Masatoshi Ohgushi

Kyoto UniversityORCID 0000-0002-1293-4893Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Mototsugu EirakuiD· 2 shared Alexis VandenboniD· 1 shared Hitoshi NiwaiD· 1 shared Kaori Honda· 1 shared Nobuko Taniyama· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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2 shared papersDevelopmental Biology

Mototsugu EirakuORCID

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintAug 4, 2025

Chromatin priming by transcription factor ELF3 confers transcriptional competence for amniotic differentiation on primed human embryonic stem cells

Masatoshi Ohgushi, Kaori Honda, Hitoshi Niwa, Mototsugu Eiraku

1 citation

humanbulk RNA-seq

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Developmental BiologyCell ReportsPeer-reviewedJun 1, 2022

Cell-autonomous differentiation of human primed embryonic stem cells into trophoblastic syncytia through the nascent amnion-like cell state

Masatoshi Ohgushi, Nobuko Taniyama, Alexis Vandenbon, Mototsugu Eiraku

This study shows that blocking ACTIVIN/NODAL and FGF signals in human pESCs leads to GATA3-expressing syncytia resembling trophoblasts, revealing a cell-autonomous differentiation pathway.

21 citations

humanbulk RNA-seq

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