Author

Marjolein T. Oostrom

Pacific Northwest National LaboratoryORCID 0000-0002-1296-9084Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Approach:large language model· 1 Assay:metabolomics· 1

Frequent Co-Authors

Bobbie‐Jo Webb‐RobertsoniD· 1 shared Jason McDermottiD· 1 shared Jaydeep P. BardhaniD· 1 shared Kasey Bowyer· 1 shared Kelly G. StrattoniD· 1 shared Lisa BrameriD· 1 shared Lummy Maria Oliveira MonteiroiD· 1 shared Michael A. MuniakiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Bobbie‐Jo Webb‐RobertsonORCID

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2 papers

Recent·Most cited

PathwaySeeker: Evidence-Grounded AI Reasoning over Organism-Specific Metabolic Networks

Lummy Maria Oliveira Monteiro, Niaz Bahar Chowdhury, Marjolein T. Oostrom, Jason McDermott, Kelly G. Stratton, Sutanay Choudhury, Jaydeep P. Bardhan

PathwaySeeker uses AI to reason about organism-specific metabolic networks using proteomic and metabolomic data, distinguishing confirmed reactions from hypotheses.

bioRxiv · Apr 17, 2026 · PreprintBioinformatics

Fine-tuning TrailMap: The utility of transfer learning to improve the performance of deep learning in axon segmentation of light-sheet microscopy images

Marjolein T. Oostrom, Michael A. Muniak, Rogene M. Eichler West, Sarah M. Akers, Paritosh Pande, Moses Y. Obiri, Wei Wang, Kasey Bowyer, Zhuhao Wu, Lisa Bramer, Tianyi Mao, Bobbie‐Jo Webb‐Robertson

This paper improves axon segmentation in light-sheet microscopy images by fine-tuning the TrailMap model with expert-labeled data, achieving better recall and adjusted F1-score.

PLoS ONE · Mar 29, 2024Peer-reviewedNeuroscience