A cross-organism framework for supervised enhancer prediction with epigenetic pattern recognition and targeted validation
Anurag Sethi, Mengting Gu, Emrah Gumusgoz, Landon Long Chan, Koon‐Kiu Yan, Joel S. Rozowsky, Iros Barozzi, Veena Afzal, Jennifer A. Akiyama, Ingrid Plajzer-Frick, Chengfei Yan, Catherine S. Novak, Momoe Kato, Tyler H. Garvin, Quan T. Pham, , Mark Gerstein
This paper develops a cross-organism framework for enhancer prediction using Drosophila STARR-seq data and supervised machine learning, validated in mouse and human with 153 enhancers.
Nature Methods · Jul 29, 2020Peer-reviewedBioinformatics