Anne N. Harrington

This study identifies exosome trafficking as a key regulator of beige adipocyte thermogenesis, showing that exosome release enhances thermogenic output and energy expenditure.

The paper shows that org1 is required for specifying niche cell identity in Drosophila testis, influencing islet to establish a functional stem cell microenvironment.

This study shows that chronic stress in male mice reduces sperm miR-34c levels through astrocyte-derived exosomes, leading to transgenerational anxiety and reduced sociability in offspring.

This study shows that deleting TAD boundaries in mice often causes molecular or developmental phenotypes, highlighting their importance for genome function.

This paper develops a cross-organism framework for enhancer prediction using Drosophila STARR-seq data and supervised machine learning, validated in mouse and human with 153 enhancers.

The paper systematically maps chromatin state landscapes during mouse development by profiling histone modifications across 72 tissue-stages, identifying dynamic enhancers and transcriptional regulators.

The paper re-evaluates the efficiency of a CRISPR-Cas9 method for generating conditional knockout alleles in mice, finding very low success rates and high rates of undesired alleles.