Author

Paul William Young

University College CorkORCID 0000-0002-1307-0249Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Nicola M. O’RiordaniD· 2 shared Vanja Jurić· 2 shared Andrew J. LindsayiD· 1 shared Aoife P. Roche· 1 shared Bálint MészárosiD· 1 shared Eamonn Maher· 1 shared Eoghan Thomas O’LearyiD· 1 shared John Fehilly· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersSynthetic Biology

Nicola M. O’RiordanORCID

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3 papers

Recent·Most cited

Yeast MoClo secretion and surface display toolkit 2.0: improvements and applications for analysis of protein-protein interactions and whole-cell biocatalysis

Vanja Jurić, Leah G Erwin, Nicola M. O’Riordan, Eamonn Maher, Justin D. Holmes, Paul William Young

The paper improves and applies a yeast secretion and display toolkit for analyzing protein interactions and whole-cell biocatalysis.

ACS Synthetic Biology · Apr 23, 2026Peer-reviewedSynthetic Biology

Condensate formation of the human RNA-binding protein SMAUG1 is controlled by its intrinsically disordered regions and interactions with 14-3-3 proteins

Olivia Carey, John Fehilly, Eoghan Thomas O’Leary, Stephen O’Shea, Klaudia Juda, Rahel Fitzel, Pooja Selvaraj, Katja Burk, Andrew J. Lindsay, Paul William Young, Rita Pancsa, Bálint Mészáros, Kellie A. Dean

This paper shows that SMAUG1 forms condensates via its disordered region and that 14-3-3 proteins dissolve these condensates through phospho-regulated interactions.

Journal of Molecular Biology · Jul 2, 2025Peer-reviewedMolecular Biology

A yeast modular cloning (MoClo) toolkit expansion for optimization of heterologous protein secretion and surface display in Saccharomyces cerevisiae.

Nicola M. O’Riordan, Vanja Jurić, Sarah K. O’Neill, Aoife P. Roche, Paul William Young

The paper expands a yeast cloning toolkit to include optimized signal peptides and surface display anchors for improved protein secretion and display in S. cerevisiae.

ACS Synthetic Biology · Mar 14, 2024Peer-reviewedSynthetic Biology