Wenting Xiang

This paper develops CPMP, a weakly supervised transformer model, to predict MammaPrint recurrence risk from breast cancer histopathological slides, achieving an AUROC of 0.824.

The paper establishes a single-cell atlas of breast cancer in young Chinese women, identifies new subtypes and therapeutic targets, and reveals distinct tumor progression patterns.

This study uses scRNA-seq and scATAC-seq to analyze cellular heterogeneity and chromatin accessibility changes in young breast cancer patients before and after neoadjuvant therapy, identifying therapy-resistant genes and signaling pathways.

NeoTCR is a database of experimentally validated neoantigen-specific TCR sequences across 18 cancer types, enabling query and analysis of TCR-clonotypes and neoantigen associations.