Cancer BiologybioRxivPreprint
Single-Cell RNA and ATAC Sequencing Reveal Cellular Heterogeneity and Chromatin Accessibility Dynamics in Young Chinese Breast Cancer Patients across Pre- and Post-Neoadjuvant Therapy
Xue Mei Han, Bin Wang, Wenting Xiang…·Jian Liu
This study uses scRNA-seq and scATAC-seq to analyze cellular heterogeneity and chromatin accessibility changes in young breast cancer patients before and after neoadjuvant therapy, identifying therapy-resistant genes and signaling pathways.