Author

Yasuo Nagafuchi

The University of TokyoORCID 0000-0002-1316-8035Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Hirofumi ShodaiD· 2 shared Kazuhiko YamamotoiD· 2 shared Kazuyoshi IshigakiiD· 2 shared Keishi FujioiD· 2 shared Akari SuzukiiD· 1 shared Aya Nishiwaki· 1 shared Chikashi C. TeraoiD· 1 shared Fuyuki MiyaiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Hirofumi ShodaORCID

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2 papers

Recent·Most cited

Cell-type-specific transcriptome architecture underlying the establishment and exacerbation of systemic lupus erythematosus

Masahiro Nakano, Mineto Ota, Yusuke Takeshima, Yukiko Iwasaki, Hiroaki Hatano, Yasuo Nagafuchi, Takahiro Itamiya, Junko Maeda, Ryochi Yoshida, Saeko Yamada, Aya Nishiwaki, Haruka Takahashi, Hideyuki Takahashi, Yuko Akutsu, Takeshi Kusuda, , Keishi Fujio

This study identifies cell-type-specific transcriptomic signatures associated with SLE disease establishment and exacerbation, highlighting their clinical relevance and potential limitations in capturing genetic risk factors.

medRxiv · Jan 12, 2022 · PreprintGenetic & Genomic Medicine

Splicing QTL analysis focusing on coding sequences reveals pathogenicity of disease susceptibility loci.

Kensuke Yamaguchi, Kazuyoshi Ishigaki, Akari Suzuki, Yumi Tsuchida, Haruka Tsuchiya, Shuji Sumitomo, Yasuo Nagafuchi, Fuyuki Miya, Tatsuhiko Tsunoda, Hirofumi Shoda, Keishi Fujio, Kazuhiko Yamamoto, Yuta Kochi

The paper analyzes splicing QTLs focusing on coding sequences to identify disease-causal variants associated with GWAS traits through novel integration and selection approaches.

bioRxiv · Dec 30, 2021 · PreprintGenetics