Cara Haymaker

This study compares spatial immune architectures in tumor and tumor-adjacent tissues of early-stage NSCLC, finding distinct immune cell densities, spatial patterns, and associations with genomic features and patient outcomes.

This study compares imaging-based spatial transcriptomics platforms using FFPE tumor samples, finding differences in performance and highlighting factors affecting data quality.

This study identifies cellular and microenvironmental factors contributing to radiation therapy resistance in pancreatic cancer using spatial transcriptomics and single-cell RNA sequencing.

The paper constructs immune-specific gene sets using non-negative matrix factorization on bulk RNA-seq data to improve immune subtype analysis and ICB response prediction.

This paper introduces LSGI, a framework to identify interpretable spatial gradients in spatial transcriptomics data, revealing pathway gradients in glioblastoma and across 87 tumor datasets.

The paper investigates how anti-cancer immunity evolves from preneoplasia to invasive lung adenocarcinomas, identifying changes in immune response and molecular features that may facilitate immune evasion.