Author

Robert H. Melde

University of Wisconsin SystemORCID 0000-0002-1325-4566Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

JoHanna M. Abraham· 2 shared Nathaniel P. SharpiD· 2 shared Austin DaigleiD· 1 shared Daniela M. Blumstein· 1 shared Madison P. Castle· 1 shared Maryn R. Ugolini· 1 shared Molly M. Fjalstad· 1 shared Sarah Durski· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 23 mutual co-author links

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2 shared papersEvolutionary Biology

JoHanna M. Abraham

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2 papers

Recent·Most cited

Evolutionary BiologyG3 Genes Genomes GeneticsPeer-reviewedJan 23, 2026

Meiotic double strand DNA breaks and spontaneous mutation in Drosophila melanogaster

Robert H. Melde, Austin Daigle, JoHanna M. Abraham, Nathaniel P. Sharp

This study investigates the relationship between meiotic double-strand breaks (DSBs) and mutation patterns in Drosophila melanogaster by comparing mutation accumulation in strains with and without DSBs.

DOI 10.1093/g3journal/jkag019

Drosophilawhole-genome sequencing

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Evolutionary BiologyEvolutionPeer-reviewedSep 15, 2024

Sex-specific viability effects of mutations in Drosophila melanogaster

Robert H. Melde, JoHanna M. Abraham, Maryn R. Ugolini…·Nathaniel P. Sharp

The paper measures sex-specific viability effects of mutations in Drosophila melanogaster and finds that both marker mutations and mutagenized chromosomes reduce viability in both sexes, with some sex-biased selection but not male-biased mutational variance.

5 citations

Drosophilaexperimental assay

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