Nathaniel P. Sharp

The paper examines spontaneous mutations affecting CUP1 copy number and copper tolerance in yeast, finding rapid copy number loss but limited phenotypic impact.

This study investigates genetic variation in trauma-induced mortality risk in Drosophila melanogaster using quantitative genetics and finds that condition-related factors significantly influence mortality outcomes.

This study shows that increased sexual selection in yeast leads to rapid evolutionary changes in mating traits and sexual differentiation.

The paper investigates mutation rate differences between haploid and diploid yeast by examining the role of REV1 in translesion synthesis, finding higher mutation rates in haploids and convergence after REV1 deletion.

This study investigates the relationship between meiotic double-strand breaks (DSBs) and mutation patterns in Drosophila melanogaster by comparing mutation accumulation in strains with and without DSBs.

The paper compares mutation rates in haploid and diploid cells of two yeast species, finding higher mutation rates in the rare cell type, supporting the drift barrier hypothesis.

This paper measures aneuploidy reversion rates in yeast using a fluctuation assay, showing fitness effects influence estimates and chromosome-specific loss rates.

The paper measures sex-specific viability effects of mutations in Drosophila melanogaster and finds that both marker mutations and mutagenized chromosomes reduce viability in both sexes, with some sex-biased selection but not male-biased mutational variance.

The study shows that mutations in yeast are deleterious on average, regardless of the testing environment's adaptation level.

The paper quantifies mutation and selection impacts on rDNA copy number variation in yeast, finding high mutational variance and stabilizing selection.