Global Identification of Direct SWI/SNF Targets Reveals Compensation by EP400
Benjamin J. E. Martin, Eileen F. Ablondi, Christine Goglia, Karen Adelman
The paper identifies direct SWI/SNF targets and reveals EP400 as a compensatory remodeler, showing synthetic lethality in cancer and predicting SWI/SNF dependence from chromatin state.
bioRxiv · Mar 7, 2023 · PreprintMolecular Biology