Benjamin J. E. Martin

This study shows Notch1 activates transcription by releasing paused RNA Pol II without requiring chromatin accessibility changes.

The paper identifies direct SWI/SNF targets and reveals EP400 as a compensatory remodeler, showing synthetic lethality in cancer and predicting SWI/SNF dependence from chromatin state.

The paper identifies sequence features that influence RNA polymerase II elongation potential by screening thousands of transcribed regions using INSERT-seq.

This study shows that most histone acetylation depends on transcription, as inhibition of transcription reduces histone acetylation and affects HAT recruitment and activity.

This study shows FACT interacts with unstable nucleosomes in transcribed regions of S. cerevisiae, dependent on transcription by any RNA polymerase.

The paper shows that H3K4 and H3K36 methylation recruit the NuA3 complex to transcribed genes in S. cerevisiae, while acetylated H3K9 does not, and that the YEATS domain of Taf14 is not involved in recruitment.