Ruiguo Yang

This paper introduces a data-driven image analysis approach to quantify antibody-induced changes in cell-cell adhesion and pathogenicity in pemphigus vulgaris.

This study shows that PV antibodies cause tension loss at desmosomes and cell-cell adhesions by inhibiting RhoA, which can be partially reversed by altering actomyosin contractility.

This study shows epithelial cells exhibit a strain-rate dependent bimodal stress response, including dynamic tensioning resembling active pulling-back, mediated by actin remodeling.