Author

Blake D. Jardin

Boston Children's HospitalORCID 0000-0002-1376-5235Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Qing MaiD· 2 shared William T. PuiD· 2 shared Yuxuan GuoiD· 2 shared Alan H. BeggsiD· 1 shared Behzad MoghadaszadehiD· 1 shared Canzhao LiuiD· 1 shared Congting GuoiD· 1 shared Emily C. Troiano· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintDec 6, 2023

In vivo proximity proteomics uncovers palmdelphin (PALMD) as a Z-line-associated mitigator of isoproterenol-induced cardiac injury

Congting Guo, Blake D. Jardin, Junsen Lin…·Yuxuan Guo

This study identifies PALMD as a Z-line-associated protein that mitigates cardiac injury through stabilization of NEXN using in vivo proximity proteomics.

DOI 10.1101/2023.12.06.570334

mousehuman

Developmental BiologybioRxivPreprintNov 13, 2019

Sarcomeres regulate cardiomyocyte maturation through MRTF-SRF signaling

Yuxuan Guo, Blake D. Jardin, Isha Sethi…·William T. Pu

This study shows that sarcomere assembly via ACTN2 and MRTF-SRF signaling promotes cardiomyocyte maturation through a positive feedback loop.

3 citations

mousebulk RNA-seq