Author

Isha Sethi

Boston Children's HospitalORCID 0000-0001-7965-0150Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Guo‐Cheng YuaniD· 2 shared Qing MaiD· 2 shared William T. PuiD· 2 shared Yuxuan GuoiD· 2 shared Aida Akaeva· 1 shared Alan H. BeggsiD· 1 shared Aleksandr SarachakoviD· 1 shared Alexander BagaeviD· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersDevelopmental Biology

Guo‐Cheng YuanORCID

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintApr 28, 2023

Single Cell Resolution Spatial Mapping of Human Hematopoiesis Reveals Aging-Associated Topographic Remodeling

Aleksandr Sarachakov, Arina Varlamova, Viktor Svekolkin…·Sanjay S. Patel

This study maps human hematopoiesis at single-cell resolution, revealing aging-associated topographic remodeling in bone marrow.

DOI 10.1101/2023.04.28.538715

humanspatial transcriptomics

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Developmental BiologybioRxivPreprintNov 13, 2019

Sarcomeres regulate cardiomyocyte maturation through MRTF-SRF signaling

Yuxuan Guo, Blake D. Jardin, Isha Sethi…·William T. Pu

This study shows that sarcomere assembly via ACTN2 and MRTF-SRF signaling promotes cardiomyocyte maturation through a positive feedback loop.

3 citations

mousebulk RNA-seq

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GeneticsbioRxivPreprintOct 17, 2019

In vivo CRISPR screening identifies RNF20/40 as epigenetic regulators of cardiomyocyte maturation

Nathan J. VanDusen, Julianna Y. Lee, Weiliang Gu…·William T. Pu

6 citations

mouseexperimental assay

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