Author

Iván D’Orso

The University of Texas Southwestern Medical CenterORCID 0000-0002-1409-2351Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ana Beatriz DePaula-SilvaiD· 1 shared Ashwini Challa· 1 shared Carlos GuzmaniD· 1 shared Christian V. ForstiD· 1 shared Emily L. Morton· 1 shared Holly RuessiD· 1 shared Jeon LeeiD· 1 shared Micah A. ThorntoniD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperMolecular Biology

Ana Beatriz DePaula-SilvaORCID

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3 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedJul 12, 2024

KAP1 negatively regulates RNA polymerase II elongation kinetics to activate signal-induced transcription

Usman Hyder, Ashwini Challa, Micah A. Thornton…·Iván D’Orso

The paper shows that KAP1 negatively regulates RNA polymerase II elongation kinetics to enhance signal-induced transcription of Immediate Early Genes.

7 citations

experimental assay

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GenomicsbioRxivPreprintMay 1, 2020

An integrated genomics approach towards deciphering human genome codes shaping HIV-1 proviral transcription and fate

Holly Ruess, Jeon Lee, Carlos Guzman…·Iván D’Orso

The paper uses integrated genomics data to identify chromatin states and nuclear compartments influencing HIV-1 proviral transcription and fate.

2 citations

humanbulk RNA-seq

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Molecular BiologyCell ReportsPeer-reviewedApr 1, 2019

Transcriptional Circuit Fragility Influences HIV Proviral Fate

Emily L. Morton, Christian V. Forst, Yue Zheng…·Iván D’Orso

The paper investigates how HIV's transcriptional circuit, which bypasses host regulatory checkpoints, is influenced by host phase fragility, affecting viral latency and reactivation.

32 citations

humanbulk RNA-seq

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