Author

Jian V. Zhang

Chinese Academy of SciencesORCID 0000-0002-1427-8957Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Chenxi GuoiD· 1 shared Dafu Zhi· 1 shared Feifei Du· 1 shared Hui HongiD· 1 shared Huicheng Chen· 1 shared Jiahuan ZhengiD· 1 shared Jiaming Wang· 1 shared Jiaping Su· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperDevelopmental Biology

Chenxi GuoORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 28, 2025

Crosstalk between Immune Microenvironment and Hair Follicle Cells Underlies Sexual Dimorphism in Androgenetic Alopecia

Feifei Du, Lei Ge, Yali Yang…·Jian V. Zhang

This study investigates sex-specific differences in androgenetic alopecia by analyzing immune-follicle interactions and identifies potential therapeutic polypeptides.

DOI 10.1101/2025.09.28.678997

mousescRNA-seq

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Developmental BiologyCommunications BiologyPeer-reviewedOct 5, 2023

ClpP/ClpX deficiency impairs mitochondrial functions and mTORC1 signaling during spermatogenesis and meiosis

Chenxi Guo, Yuan Xiao, Jingkai Gu…·Tianren Wang

This study shows ClpP/ClpX deficiency impairs mitochondrial function and mTORC1 signaling in spermatocytes, leading to meiotic defects and reduced testicular size.

16 citations

mouseexperimental assay

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Developmental BiologyPLoS GeneticsPeer-reviewedJun 11, 2021

An extracellular protein regulates patched-related/DAF-6-mediated sensory compartment formation in C. elegans

Hui Hong, Huicheng Chen, Yuxia Zhang…·Qing Wei

This study identifies DYF-4 as a glia-secreted protein that interacts with DAF-6 to regulate glial channel formation and neuronal development in C. elegans.

5 citations

C. elegansexperimental assay

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