Jian Ming Khor

The paper introduces an EpiTag zebrafish transgenic reporter to visualize epigenetic silencing/activation and identifies tissue-specific epigenetic regulatory genes through mutagenesis screening.

The paper uses a novel transgenic reporter to study epigenetic reprogramming during zebrafish fin regeneration, identifying early chromatin remodeling events and key factors required for regeneration.

The paper investigates protein mobility in sea urchin skeletogenic syncytia and finds that transcription factors and biomineralization proteins have restricted mobility, contributing to molecular compartmentalization.

The paper optimizes a Tet-On system for conditional gene expression in sea urchins and demonstrates its utility in studying MAPK signaling in skeletogenesis.

The paper identifies conserved cis-regulatory elements and transcription factor inputs for the kirrelL gene across echinoderm species, showing stability of GRN sub-circuits over 500 million years.