Author

Justin W. Mabin

National Institutes of HealthORCID 0000-0002-1434-0597Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:software / tool· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Alexandra ZhangiD· 2 shared Isaac W. VockiD· 2 shared J. Robert HoggiD· 2 shared Martin MachynaiD· 2 shared Matthew D. SimoniD· 2 shared Ganesha RaiiD· 1 shared Guramrit SinghiD· 1 shared Isabelle Nathalie-Marie LeibleriD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMolecular Biology

Alexandra ZhangORCID

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3 papers

Recent·Most cited

Molecular BiologyGenome biologyPeer-reviewedJul 15, 2026

Uncovering the isoform-resolution kinetic landscape of nonsense-mediated mRNA decay with EZbakR

Justin W. Mabin, Isaac W. Vock, Martin Machyna…·J. Robert Hogg

The paper introduces a method to infer isoform-level kinetics of nonsense-mediated mRNA decay using short-read NR-seq data, revealing variability in NMD efficiency and decay rates of transcripts with and without PTCs.

6 citations

bulk RNA-seqstatistical model

𝕏 PostBluesky

BioinformaticsPLoS Computational BiologyPeer-reviewedJul 3, 2025

Expanding and improving analyses of nucleotide recoding RNA-seq experiments with the EZbakR suite

Isaac W. Vock, Justin W. Mabin, Martin Machyna…·Matthew D. Simon

The paper introduces EZbakR and fastq2EZbakR tools to enhance NR-seq data analysis by supporting multi-label modeling, improved variance accounting, and flexible statistical comparisons.

10 citations

bulk RNA-seqstatistical model

𝕏 PostBluesky

Molecular BiologyCell ReportsPeer-reviewedNov 1, 2018

The exon junction complex undergoes a compositional switch that alters mRNP structure and nonsense-mediated mRNA decay activity

Justin W. Mabin, Lauren A. Woodward, Robert D. Patton…·Guramrit Singh

The paper shows the exon junction complex (EJC) undergoes a compositional switch from an SR-rich to an SR-devoid form, altering mRNP structure and NMD activity.

84 citations

humanmultiome

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