IRIS: Big data-informed discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing
Yang Pan, John W. Phillips, Beatrice D. Zhang, Miyako Noguchi, Eric Kutschera, Jami McLaughlin, Pavlo A. Nesterenko, Zhiyuan Mao, Nathanael Joshua Bangayan, Robert Wang, Wendy Tran, Harry Taegyun Yang, Yuanyuan Wang, Yang Xu, Matthew B. Obusan, , Yi Xing
IRIS identifies cancer immunotherapy targets from alternative splicing using transcriptomics data and validates them with patient T cells.
Proceedings of the National Academy of Sciences · May 16, 2023Peer-reviewedBioinformatics