Author

Cristina Puig-Saus

University of California, Los AngelesORCID 0000-0002-3014-3649Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Bioengineering· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Antoni RibasiD· 4 shared Abby Anderson· 1 shared Alan AshworthiD· 1 shared Alex LeeiD· 1 shared Alexander MarsoniD· 1 shared Alexandria M. Duven· 1 shared Ameya S. ChamphekariD· 1 shared Amy L. PutnamiD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersBioinformatics

Antoni RibasORCID

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4 papers

Recent·Most cited

BioengineeringbioRxivPreprintApr 21, 2025

Whole-Proteome Screening and Multi-Modal Profiling of Antigen-Specific CD4+ T Cells at Single-Cell Resolution

Rongyu Zhang, Qi Jin, Michaela McKasson…·James R. Heath

The paper develops a high-throughput platform to profile antigen-specific CD4+ T cells at single-cell resolution, identifying immunogenic features and functional heterogeneity in viral and cancer contexts.

DOI 10.1101/2025.04.21.649828

humanproteomics

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BioinformaticsProceedings of the National Academy of SciencesPeer-reviewedMay 16, 2023

IRIS: Big data-informed discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing

Yang Pan, John W. Phillips, Beatrice D. Zhang…·Yi Xing

IRIS identifies cancer immunotherapy targets from alternative splicing using transcriptomics data and validates them with patient T cells.

51 citationstop 2%

humanbulk RNA-seq

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BioinformaticsScience ImmunologyPeer-reviewedApr 7, 2023

Computational prediction of MHC anchor locations guide neoantigen identification and prioritization

Huiming Xia, Joshua F. McMichael, Michelle Becker‐Hapak…·Malachi Griffith

The paper predicts MHC anchor positions for 328 HLA alleles and shows that incorporating these improves neoantigen identification by correcting misclassified candidates in tumor samples.

30 citations

humanbulk RNA-seq

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GeneticsNaturePeer-reviewedJul 1, 2018

Reprogramming human T cell function and specificity with non-viral genome targeting

Theodore L. Roth, Cristina Puig-Saus, Ruby Yu…·Alexander Marson

This paper develops a non-viral CRISPR-Cas9 system for precise genome editing in human T cells, enabling therapeutic reprogramming of cell function and specificity.

839 citationstop 1%

humanexperimental assay

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