Author

Matthew R. Reynolds

University of Wisconsin–MadisonORCID 0000-0002-1484-6408Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:DNA methylation· 1 Organism:non-human primate· 1 Organism:rat· 1

Frequent Co-Authors

Andrew Conchas· 1 shared Brandon F. KeeleiD· 1 shared Corina C. Valencia· 1 shared Ethan P. Johnson· 1 shared Lea M. MatschkeiD· 1 shared Olivia E. HarwoodiD· 1 shared Ryan V. MoriartyiD· 1 shared Shelby L. O’ConnoriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

Andrew Conchas

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintNov 18, 2025

CD8α+ cells suppress SIV replication without evidence of viral immune escape during post treatment control

Ryan V. Moriarty, Olivia E. Harwood, Ethan P. Johnson…·Shelby L. O’Connor

This study shows CD8α+ cells suppress SIV replication without immune escape in post-treatment controllers, using a macaque model and barcoded viral sequencing.

DOI 10.1101/2025.11.18.689043

non-human primateDNA methylation

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ImmunologybioRxivPreprintApr 22, 2025

Modeling simian immunodeficiency virus (SIV) latency in primary rhesus macaque CD4+ T cells

Lea M. Matschke, Matthew R. Reynolds

This paper develops an in vitro model of SIV latency in rhesus macaque CD4+ T cells, generating latently infected cells that mimic in vivo reservoirs and enabling studies of latency mechanisms and cure strategies.

DOI 10.1101/2025.04.22.650029

ratexperimental assay

𝕏 PostBluesky