Physical activity reduces colorectal cancer risk independent of BMI - A two-sample Mendelian randomisation study
Xiaomeng Zhang, Evropi Τheodoratou, Xue Li…·Maria N Timofeeva
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University of CambridgeORCID 0000-0002-1495-2470Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Xiaomeng Zhang, Evropi Τheodoratou, Xue Li…·Maria N Timofeeva
Golam Mohammed Khandaker, Verena Zuber, Jessica M. B. Rees…·Stephen Burgess
This study investigates shared mechanisms between coronary heart disease and depression using UK Biobank data, finding that environmental factors and specific biomarkers like IL-6, CRP, and triglycerides are likely causal for depression.
Stephen Burgess, Verena Zuber, Apostolos Gkatzionis…·Christopher N. Foley
This paper introduces a heterogeneity-penalized model averaging method for Mendelian randomization that improves efficiency and Type 1 error control when multiple valid instruments are present.