Man Soo Kim

The paper identifies CPT1B-mediated fatty acid oxidation as a driver of pigmentation in solar lentigo through multi-omics analysis and zebrafish modeling.

This study uses multi-omics analysis of bulk and single-cell RNA-seq data from pterygium patients to identify region-specific transcriptomic signatures and the role of epithelial cells in inflammation.

This study generates ndufs2-/- zebrafish with CI deficiency, showing metabolic and neuromuscular defects treatable by folic acid.

This study investigates how SARS-CoV-2 infection affects mitochondrial gene expression in different tissues and disease stages, finding targeted inhibition in some organs and upregulation in others.

Scedar is a Python package for scRNA-seq exploratory analysis, offering visualization, imputation, rare profile detection, and clustering on large datasets efficiently and without distribution assumptions.

The paper develops a method to simulate cellular metabolism using scRNA-seq data and validates it with NAD+ biosynthesis flux measurements in mouse tissues.