Author
Children's Hospital of PhiladelphiaORCID 0000-0001-6700-3378Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Robert T. Steinbock, Orlando Bonito Scudero, Joseph M. Dybas…·Matthew D. Weitzman
This study shows adenovirus mutants differentially activate dsRNA sensors, leading to distinct RNP granule assemblies via PKR and OAS3/RNase L pathways.
Ammar S. Naqvi, Patricia J. Sullivan, Ryan J. Corbett…·Jo Lynne Rokita
The paper analyzes splicing in 729 pediatric brain tumors, identifies splicing-defined subgroups, and highlights CLK1 exon 4 as an oncofetal event linked to tumor prognosis.
Zhuangzhuang Geng, Eric K. Wafula, Ryan J. Corbett…·Jo Lynne Rokita
The paper introduces OpenPedCan, a harmonized multi-omic dataset of pediatric cancer patients, providing integrated genomic, transcriptomic, and proteomic data for research and clinical applications.
Joseph W. Guarnieri, Joseph M. Dybas, Hossein Fazelinia…·Douglas C. Wallace
This study investigates how SARS-CoV-2 infection affects mitochondrial gene expression in different tissues and disease stages, finding targeted inhibition in some organs and upregulation in others.
Jackie McDonald, Francisco J. Enguita, Deanne M. Taylor…·Afshin Beheshti
The paper identifies miR-2392 as a miRNA involved in SARS-CoV-2 infection, showing its role in inflammation, glycolysis, and hypoxia, and develops a miRNA-based therapeutic targeting it.