Zhaohao Liao

SPIRFISH detects protein and RNA in single nanoparticles, revealing variability in structure and RNA packaging efficiency.

This study profiles miRNAs in primate cervicovaginal lavage and EVs during the menstrual cycle and SIV infection, identifying miR-186-5p as a potential retroviral restriction factor in macrophages.

The paper investigates the distribution of miR-21 between HMW-RISC and LMW-RISC fractions in thyroid cancer cell lines and finds miR-21 is more enriched in LMW-RISC.

This study shows that serum extracellular vesicle depletion affects HIV-1 production and infectivity in cell cultures, with potential confounding effects from other particles.