Xiang Wang

ERAD Activity Distinguishes the Functional Heterogeneity of Hematopoietic Stem Cells

This study identifies ERAD activity as a predictive and heritable marker of hematopoietic stem cell function by linking cytokine signaling to proteostasis remodeling.

GASPS: A Multi-Omics Framework for Defining Genomic Aberration-Driven Signatures and Predicting Patient Outcomes in Lung Cancer

GASPS develops a statistical framework to define genomic aberration-driven signatures and predict patient outcomes in lung cancer using transcriptomic data.

Isoliensinine Ameliorates Pathological Cardiac Hypertrophy After Aerobic Exercise by Activating Cytochrome c Oxidase Subunit 6A2

This study identifies isoliensinine's role in improving cardiac function by enhancing COX6A2 expression through swimming exercise, revealing a novel signaling axis in pathological cardiac hypertrophy.

NOLC1 Suppresses Immuno-chemotherapy by Inhibiting p53-mediated Ferroptosis in Gastric Cancer

This study shows that NOLC1 suppresses cisplatin chemotherapy and immune checkpoint inhibitor therapy in gastric cancer by inhibiting p53-mediated ferroptosis.