ERAD Activity Distinguishes the Functional Heterogeneity of Hematopoietic Stem Cells
Qinlu Peng, Manxi Zheng, Suxuan Liu, Xinshu Xie, Zhejuan Shen, Ting Wang, Hanqi Liu, Wenbin Mi, Jie Zhou, Xuezhen Ma, Zhenyou Yin, Yuhan Hu, Guojun Shi, Yewei Ji, Dingxiao Zhang, , Lu Liu
This study identifies ERAD activity as a predictive and heritable marker of hematopoietic stem cell function by linking cytokine signaling to proteostasis remodeling.
bioRxiv · Dec 5, 2025 · PreprintCell Biology