Author

Robert Taylor Ripley

Baylor College of MedicineORCID 0000-0003-0053-307XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Chao ChengiD· 2 shared Christopher Ian AmosiD· 2 shared Jia WuiD· 2 shared Abhinav K. JainiD· 1 shared Atsushi Ito· 1 shared Ayu Hutami SyarifiD· 1 shared Bryan M. BurtiD· 1 shared Chenyang LiiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBioinformatics

Chao ChengORCID

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4 papers

Recent·Most cited

ImmunologyJournal of Thoracic and Cardiovascular SurgeryPeer-reviewedMar 4, 2026

Tumor-infiltrating natural killer cell profiling for therapeutic stratification in patients with resectable non-small cell lung cancer

Atsushi Ito, Sung Wook Kang, Hee-Jin Jang…·Hyun-Sung Lee

This study identifies smoking-associated natural killer cell subsets in NSCLC that correlate with survival and response to neoadjuvant chemoimmunotherapy, suggesting their use in therapeutic stratification.

1 citation

humanscRNA-seq

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BioinformaticsInternational Journal of CancerPeer-reviewedDec 16, 2025

Gene signatures characterizing driver mutations in lung squamous carcinoma are predictive of the progression of pre-cancer lesions

Yupei Lin, Venugopala Reddy Mekala, Jianrong Li…·Chao Cheng

This study develops gene expression signatures from LUSC tumors to predict progression risk of precancerous lesions, finding they outperform genomic aberrations in prognosis and correlate with immune features.

1 citation

humanbulk RNA-seq

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BioinformaticsbioRxivPreprintAug 21, 2025

GASPS: A Multi-Omics Framework for Defining Genomic Aberration-Driven Signatures and Predicting Patient Outcomes in Lung Cancer

Zijian Zhang, Xiang Wang, Chenyang Li…·Chao Cheng

GASPS develops a statistical framework to define genomic aberration-driven signatures and predict patient outcomes in lung cancer using transcriptomic data.

1 citation

humanbulk RNA-seq

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Systems BiologybioRxivPreprintMar 21, 2021

SMARCA4 regulates spatially restricted metabolic plasticity in 3D multicellular tissue

Kateřina Čermáková, Eric A. Smith, Yuen San Chan…·H. Courtney Hodges

This study shows that SMARCA4 regulates spatially restricted metabolic changes in 3D multicellular tissues by altering DNA accessibility and gene expression.

4 citations

humanscRNA-seq

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