Steve C. N. Hui

Age-related differences in neurometabolite concentrations during early infancy: A cross-sectional analysis of the HBCD Release 1.0

The paper analyzes age-related changes in neurometabolite concentrations in infants using 1H-MRS data from the HBCD study, finding significant increases in some metabolites and decreases in others.

Age dependency of neurometabolite T1 relaxation times

The paper measures metabolite T1 relaxation times in healthy adults across age groups and finds age-related decreases in several metabolites in specific brain regions.

Metabolite T2 relaxation times decrease across the adult lifespan in a large multi-site cohort

The paper investigates age-related changes in metabolite T2 relaxation times across the adult lifespan in a multi-site cohort, finding significant declines in several metabolites with aging.

A Water Relaxation Atlas for Age and Region specific Metabolite Concentration Correction

This paper develops a water relaxation atlas to correct metabolite concentrations in MRS by integrating age and region-specific relaxation values into the analysis workflow.

Integrated Short-TE and Hadamard-edited Multi-Sequence (ISTHMUS) for Advanced MRS

The paper evaluates the ISTHMUS MRS sequence for reproducibility and data quality in the HBCD study, finding improved T2 correction and reduced operator workload.

Impact of acquisition and modeling parameters on test-retest reproducibility of edited GABA+

This study evaluates how acquisition and modeling parameters affect test-retest reproducibility of GABA+ measurements using edited MRS, finding that model selection significantly impacts reproducibility.

sLASER and PRESS Perform Similarly at Revealing Metabolite-Age Correlations

This study compares PRESS and sLASER for detecting metabolite-age correlations in brain regions, finding similar results despite technical differences.

Metabolite T1 relaxation times differ across the adult lifespan

The paper examines age-related changes in metabolite T1 relaxation times in brain regions using a cross-sectional dataset and finds significant decreases in white-matter-rich areas with age.

Neurometabolic timecourse of healthy aging

The paper investigates neurometabolic changes with age using MR spectroscopy in a cross-sectional cohort, finding age correlations for several metabolites but not others.

Cohort-mean measured macromolecules lead to more robust linear-combination modeling than subject-specific or parameterized ones

This study compares metabolite estimation using different macromolecular modeling strategies and finds that cohort-mean measured MM basis functions yield more robust results than subject-specific or parameterized ones.

Dysconnectivity between auditory-cognitive network associated with auditory GABA and glutamate levels in presbycusis patients

This study investigates dysconnectivity in the auditory-cognitive network and its relation to GABA and glutamate levels in presbycusis patients, linking neurochemical changes to cognitive impairment.