Eric C. Porges

The paper assesses brain-predicted age differences in cognitively-intact oldest-old adults and finds no association between brain aging and cognitive performance or health history, suggesting high cognitive reserve and survivorship effects.

The paper measures metabolite T1 relaxation times in healthy adults across age groups and finds age-related decreases in several metabolites in specific brain regions.

The paper examines age-related GABA level changes in cognitively-intact oldest-old adults, finding that GABA decline flattens after age 80, suggesting a link between GABAergic function and successful cognitive aging.

The paper investigates age-related changes in metabolite T2 relaxation times across the adult lifespan in a multi-site cohort, finding significant declines in several metabolites with aging.

This paper develops a water relaxation atlas to correct metabolite concentrations in MRS by integrating age and region-specific relaxation values into the analysis workflow.

The paper investigates neurometabolic changes with age using MR spectroscopy in a cross-sectional cohort, finding age correlations for several metabolites but not others.

The paper examines the relationship between hippocampal structure and episodic memory in oldest-old adults, finding a significant correlation between hippocampal morphology and memory performance.

This study examines how network segregation in the brains of healthy oldest-old adults relates to cognitive performance and processing speed.

This study integrates 8 datasets to model the lifespan trajectory of cortical GABA levels, finding an early rapid increase, followed by stability and a gradual decline in adulthood and aging.

This study finds higher brain glutathione levels in older adults and links sensorimotor GSH to poorer motor performance, suggesting age-related antioxidant upregulation.

This study finds smaller limbic brain volumes are associated with greater immunosuppression in HIV+ adults across five continents.