Developmental BiologyBiochimica et Biophysica Acta (BBA) - Gene Regulatory MechanismsPeer-reviewed
Transposon insertion causes ctnnb2 transcript instability that results in the maternal effect zebrafish ichabod (ich) mutation
Zsombor Varga, Ferenc Kagan, Shingo Maegawa…·Máté Varga
The paper identifies a transposon insertion in the 3UTR of ctnnb2 as the cause of the maternal-effect ich mutation in zebrafish, leading to transcript instability and ventralized embryos.
DOI 10.1016/j.bbagrm.2025.195104