Author

Sam Gottlieb

Virginia Commonwealth UniversityORCID 0000-0002-2342-0900Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 1 Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:benchmark study· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Brennen O'Rourke· 2 shared Michael F. MilesiD· 2 shared Walker D. RogersiD· 2 shared Alanna Morgan· 1 shared Andrew D. van der VaartiD· 1 shared Anna BenrickiD· 1 shared Annalise Hassan· 1 shared Annika ThorselliD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPharmacology & Toxicology

Brennen O'Rourke

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 26, 2025

Tirzepatide attenuates dopamine reward signaling and suppresses alcohol drinking and relapse-like behaviors in rodents

Christian E. Edvardsson, Louise Adermark, Sam Gottlieb…·Elisabet Jerlhag

This study shows tirzepatide reduces alcohol consumption and relapse-like behaviors in rodents by affecting reward systems and metabolic parameters.

1 citation

mouseexperimental assay

𝕏 PostBluesky

Pharmacology & ToxicologyAddiction BiologyPeer-reviewedMay 1, 2025

A selective GSK3β inhibitor, tideglusib, decreases intermittent access and binge ethanol self-administration in C57BL/6J mice

Sam Gottlieb, Andrew D. van der Vaart, Annalise Hassan…·Michael F. Miles

This study shows that tideglusib, a GSK3β inhibitor, reduces ethanol consumption in mice without affecting water intake or anxiety-like behavior.

5 citations

mousebulk RNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintApr 3, 2025

GSK3B inhibition partially reverses brain ethanol-induced transcriptomic changes in C57BL/6J mice: Expression network co-analysis with human genome-wide association studies

Sam Gottlieb, Dustin Zeliff, Brennen O'Rourke…·Michael F. Miles

The paper investigates how GSK3B inhibition with tideglusib reverses ethanol-induced transcriptomic changes in mouse brains and links these findings to human genetic risk for alcohol dependence.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky