Molecular BiologybioRxivPreprint
The cancer-associated RBM39 bridges the pre-mRNA, U1 and U2 snRNPs to regulate alternative splicing
Sébastien Campagne, Daniel Jutzi, Florian Malard…·Frédéric H.‐T. Allain
This study identifies RBM39's role in autoregulating its own pre-mRNA splicing through interactions with U1 and U2 snRNPs, offering insights for alternative cancer therapies.
DOI 10.1101/2022.08.30.505862