Author

Martino Colombo

University of BernORCID 0000-0001-5433-2623Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 2 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Marc‐David RueppiD· 2 shared Agata StępieńiD· 1 shared Andrzej Miroslaw PacakiD· 1 shared Anne‐Christine UldryiD· 1 shared Daniel JutziiD· 1 shared Florian MalardiD· 1 shared Frédéric H.‐T. AllainiD· 1 shared Izabela MakałowskaiD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMolecular Biology

Marc‐David RueppORCID

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3 papers

Recent·Most cited

Molecular BiologyNAR CancerPeer-reviewedJun 9, 2023

Inhibition of nonsense-mediated mRNA decay reduces the tumorigenicity of human fibrosarcoma cells

Sofía Nasif, Martino Colombo, Anne‐Christine Uldry…·Oliver Mühlemann

This study shows that inhibiting NMD reduces tumorigenicity in HT1080 fibrosarcoma cells by lowering MMP9 expression, suggesting NMD inhibition as a potential cancer therapy.

16 citations

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintAug 30, 2022

The cancer-associated RBM39 bridges the pre-mRNA, U1 and U2 snRNPs to regulate alternative splicing

Sébastien Campagne, Daniel Jutzi, Florian Malard…·Frédéric H.‐T. Allain

This study identifies RBM39's role in autoregulating its own pre-mRNA splicing through interactions with U1 and U2 snRNPs, offering insights for alternative cancer therapies.

DOI 10.1101/2022.08.30.505862

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintFeb 4, 2019

FUS controls the processing of snoRNAs into smaller RNA fragments that can regulate gene expression

Patrycja Plewka, Michał Wojciech Szcześniak, Agata Stępień…·Katarzyna Dorota Raczyńska

The paper shows FUS regulates snoRNA processing into sdRNAs, which can influence gene expression and may serve as biomarkers.

5 citations

humanbulk RNA-seq

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