Author

Thomas S. Leyh

Albert Einstein College of MedicineORCID 0000-0002-1541-5204Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ian Thomas Cook· 1 shared

Activity by Year

2026-2026 · peak 1/yr

1 paper

Recent·Most cited

BiochemistrybioRxivPreprintJun 4, 2026

On the Distribution of Free-Energy in Metabolism

Ian Thomas Cook, Thomas S. Leyh

The paper investigates how half-site reactivity in enzymes allows metabolic reactions to redistribute chemical potential, enhancing catalytic efficiency and pathway flexibility.

DOI 10.64898/2026.06.01.729314

metabolomicsexperimental assay

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