Author

Keemo Delos Santos

University Health Network

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Mohit KapooriD· 2 shared Akihiro Nakamura· 1 shared Anca Maglaviceanu· 1 shared Anna De Palma· 1 shared Boris HinziD· 1 shared Brian WuiD· 1 shared Chiara PastrelloiD· 1 shared Christine YergeauiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersPharmacology & Toxicology

Mohit KapoorORCID

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3 papers

Recent·Most cited

microRNA-544a as a new modulator of the Wnt-signalling network in the articular cartilage and osteoarthritis

Cíntia Scucuglia Heluany, Nicholas James Day, Keemo Delos Santos, Anna De Palma, Tracey Swingler, Katrina Hueniken, David Sochart, Ian M. Clark, Mohit Kapoor, Giovanna Nalesso

This study identifies miR-544a as a modulator of Wnt signaling in OA chondrocytes, showing it enhances Wnt activation and promotes catabolism.

Osteoarthritis and Cartilage · Feb 26, 2026Peer-reviewedPharmacology & Toxicology

Identification of Ephrin type-B receptor 4 as a critical mediator of tissue fibrosis

Brian Wu, Starlee S. Lively, Shabana Vohra, Noah Fine, Chiara Pastrello, Anca Maglaviceanu, Osvaldo Espin-Garcia, Evan Pollock-Tahiri, Sayaka Nakamura, Paramvir Kaur, Keemo Delos Santos, Jason S. Rockel, Pratibha Potla, Himanshi Gupta, Poulami Datta, , Mohit Kapoor

This study identifies EphB4 as a critical mediator of pulmonary fibrosis through genetic and pharmacological approaches, showing reduced ECM gene expression and fibrotic pathology.

JCI Insight · Dec 21, 2025Peer-reviewedPathology

Patient-derived phosphoribosyl pyrophosphate synthetase mutations in Drosophila result in autophagy and lysosome dysfunction

Keemo Delos Santos, Christine Yergeau, Nam-Sung Moon

This study shows that patient-derived PRPS mutations in Drosophila cause autophagy and lysosome dysfunction, leading to sensitivity to nutrient deprivation and oxidative stress.

bioRxiv · Oct 9, 2018 · PreprintGenetics