Muriel Perron

This study shows that different cellular sources can regenerate the retina in Xenopus depending on the severity of injury, with RPE cells reprogramming into a mini-retina structure.

The paper investigates ROS signaling in Xenopus retinal stem cells, showing NOX promotes quiescence-to-proliferation transition by modulating Wnt/Hedgehog signaling.

This study shows Yap regulates DNA replication dynamics and interacts with Rif1 to control replication timing in early embryos and stem cells.

This study shows that Yap conditional knockout mice develop glaucoma features, including optic nerve degeneration and retinal ganglion cell death, highlighting YAP's role in preventing glaucoma.

This study shows that GSK3 signaling regulates the genesis of displaced ganglion cells in the retina, with loss of GSK3 leading to increased numbers of these cells and altered axon projections.

This study investigates Yap haploinsufficiency in mice, revealing its role in Müller glia dysfunction and late-onset cone dystrophy in aged individuals.

This study identifies YAP's role in Müller glia quiescence exit and regeneration by linking it to EGFR signaling and cell cycle re-entry in retinal injury.