MicrobiologyNature MicrobiologyPeer-reviewed
Multigenerational Proteolytic Inactivation of Restriction Upon Subtle Genomic Hypomethylation
Esther Shmidov, Alexis Villani, Senén D. Mendoza…·Ehud Banin
This study shows that Pseudomonas aeruginosa inactivates its type I R-M system via proteolysis at high temperatures, leading to prolonged genomic hypomethylation and a memory effect lasting over 60 generations.
4 citations