Author

Graham J. Tizzard

University of SouthamptonORCID 0000-0002-1577-5779Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Christopher R. M. AsquithiD· 2 shared Tuomo LaitineniD· 2 shared Alison D. AxtmaniD· 1 shared Antti PosoiD· 1 shared Carla Alamillo-Ferrer· 1 shared Carla Alamillo‐FerreriD· 1 shared Carrow I. WellsiD· 1 shared Chad D. Torrice· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

Christopher R. M. AsquithORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyEuropean Journal of Medicinal ChemistryPeer-reviewedApr 1, 2024

Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships

Christopher R. M. Asquith, Michael P. East, Tuomo Laitinen…·Gary L. Johnson

The paper identifies and optimizes narrow-spectrum TLK2 inhibitors using QSAR analysis and structural studies.

4 citations

statistical modeldrug response / drug discovery

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivPreprintFeb 11, 2019

Design and evaluation of novel 4-anilinoquinolines and quinazolines as EGFR inhibitors in lung cancer and chordoma

Christopher R. M. Asquith, Kaitlyn A. Maffuid, Tuomo Laitinen…·William J. Zuercher

The paper designs and evaluates novel 4-anilinoquinolines and quinazolines as EGFR inhibitors, identifying a potent compound for lung cancer and chordoma treatment.

DOI 10.1101/545525

humanexperimental assay

𝕏 PostBluesky