ImmunologybioRxivPreprint
Structure-function profiling identifies determinants of TCR-T cell therapeutic efficacy
Leire Oyon-Olea, Enric Vercher, Maria Gilda Dichiara-Rodriguez…·Jacinto López‐Sagaseta
The paper identifies structural and functional determinants of TCR efficacy in adoptive T-cell therapy by comparing two GPC3-specific TCRs using structural and functional assays.
DOI 10.64898/2026.09.15.750028