Author
Universidad Pública de Navarra (UPNA)ORCID 0000-0003-1560-9671Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Leire Oyon-Olea, Enric Vercher, Maria Gilda Dichiara-Rodriguez…·Jacinto López‐Sagaseta
The paper identifies structural and functional determinants of TCR efficacy in adoptive T-cell therapy by comparing two GPC3-specific TCRs using structural and functional assays.
Elena Erausquin, Maria Gilda Dichiara-Rodriguez, Leire Oyon-Olea, Jacinto López‐Sagaseta
The paper presents the first experimental structure of an Alzheimer's Aβ peptide bound to an HLA molecule, revealing key interactions and polymorphic binding sites.
Leire Oyon-Olea, Maria Gilda Dichiara-Rodriguez, Sandra Hervás‐Stubbs…·Jacinto López‐Sagaseta
This paper describes a simplified method for producing soluble TCRs in CHO cells with deglycosylation, enabling structural studies of TCR-pMHC complexes with high efficiency.
Alejandro Urdiciain, Thomas Madej, Jiyao Wang…·Jacinto López‐Sagaseta
The paper identifies novel Ig-domain features in Porifera, suggesting potential primitive adaptive immunity mechanisms.