Molecular BiologyNucleic Acids ResearchPeer-reviewed
Dynamics of the HD regulatory subdomain of PARP 1; substrate access and allostery in PARP activation and inhibition.
Tom E. H. Ogden, Ji‐Chun Yang, Marianne Schimpl…·David Neuhaus
This study investigates the dynamics of the HD subdomain in PARP-1 using NMR and crystal structures to understand its role in activation and inhibition.
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